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A 1year randomized doubleblind study
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There are some antioxidant-effective enzymes as a protective system in the organism against this damage [16]
A previous report showed that activated glial cells can participate in the death of dopaminergic neurons, probably by the activation of apoptosis by cytokines like TNF-, IL-1B, IL-6 and interferon- and the subsequent production of nitric oxide (NO) by the iNOS that may diffuse toward the neurons and induce lipid peroxidation, DNA strands breaks and inhibition of mitochondrial metabolism [6,10]
It is the only enzyme in the GPX family that directly reduces and destroys lipid hydroperoxides