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Glycocalyx heparan sulfate cleavage promotes endothelial cell angiopoietin-2 expression by impairing shear stress-related AMPK/FoxO1 signaling

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While not a traditional IgE allergy, it is a T2-high response that occurs in ~7% of asthma patients.[ref] Smoking-induced asthma: Just like it sounds cigarette smoking can be a major cause of asthma

D.BassettP.AbbaraA.et al (2023a)