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Gradual dose escalation over 4-8 weeks allows assessment of individual response and tolerance

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In OS conditions, the capacity of RBCs to reduce GSSG to GSH decreases, leading to GSSG accumulation and, consequently, to GSH depletion [14]

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Once the acylcarnitine is formed, a specialized carrier protein called Carnitine-Acylcarnitine Translocase (CACT) shuttles it across the inner mitochondrial membrane and into the mitochondrial matrix

Stakeholder Engagement : Building robust communication frameworks for members, providers and regulatory bodies