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Int J Endocrinol 2023:4288004 Hong L, Xiao S, Diao L et al (2024) Decreased AMPK/SIRT1/PDK4 induced by androgen excess inhibits human endometrial stromal cell decidualization in PCOS

GLP-1 medications can be effective while patients remain on them, but gastric sleeve often provides more durable long-term weight loss and does not depend on indefinite treatment

Serious side effects are rare when treatments are properly administered and monitored

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Growth hormone may increase insulin resistance in some patients, while GLP-1 agonists typically improve it