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About ESSENCE (semaglutide 2.4 mg) ESSENCE is a Phase 3 trial evaluating the effect of once-weekly subcutaneous semaglutide 2.4 mg in adults with metabolic dysfunction-associated steatohepatitis with moderate to advanced liver fibrosis (stage 2 or 3)

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FIGURE 1 The Hgf/c-Met Axis Hepatocyte growth factor was originally discovered in in vitro experiments as a hepatocyte mitogen (Stoker et al., 1987)