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Specifically, increased pro-inflammatory M1 macrophages and decreased M2 macrophages disrupt the cytokine milieu required for stromal decidualization, while endometrial macrophages exhibit defective phagocytic capacity and pro-inflammatory phenotypes

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In cases of very high expression levels (e.g., 50mg protein/liter), up to 2ml of resin per liter of culture may be needed

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Lack of it is like having your car stall before a big race, leaving you open to all sorts of health potholes