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As 26S was known to target NRF2 for degradation, it is postulated that reducing NRF2 degradation might result in high levels of NRF2 expression which confers the growth advantage to CSCs [130]

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Chng oxy ha mnh m: Glutathione l mt trong nhng cht chng oxy ha quan trng nht ca c th, gip bo v t bo da khi tc hi ca gc t do

Low protein intake, limited cysteine or glycine, selenium deficiency, mitochondrial dysfunction and poor glutathione recycling may further reduce antioxidant reserve

Selenium shortage worsens hyperthyroidism in the thyroid gland and upsets the microbial equilibrium essential for the gland to perform its functions correctly [57]

Its important, though, only to use it as a short-term treatment (for a maximum of three months) since its not known if its safe to use in the long term [10]