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In the context of EDC, elevated LPS levels caused by gut microbiota dysbiosis can be considered a third hit. Building upon existing central pathologies, this third hit exacerbates neuroinflammation, synergistically worsening both epileptic seizures and depressive symptoms, thereby perpetuating a vicious cycle (Arora et al., 2022)

The symptoms of a B-12 deficiency include numbness or tingling of the extremities, fatigue, weakness, anemia, swollen tongue, jaundice, difficulty walking, cognitive difficulties, memory loss and paranoia

Evaluation: body fat, body weight, lipid markers

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J Hum Genet 55:565570

Glutathione stability of erythrocytes in Iranians