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Over one-quarter of people over the age of 65 years have diabetes, and one-half of older adults have prediabetes, with prevalence expected to increase over the coming decades

Funding This research was funded by a grant funded by the Ministry of SMEs and Startups ( grant number S3275648

they are increasingly functioning as both substitutes and complements to high-margin surgical procedures

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For example, cultured astrocytes subjected to oxygen and glucose deprivation showed a decrease in mitochondrial membrane potential, possibly caused by the mitochondrial permeability transition pore (mtPTP) opening, which leads to a loss of intramitochondrial contents, mitochondrial respiration and ATP production [48]