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3.2.3 FUNDC1 mediated mitophagy The FUN14 domain-containing protein 1 (FUNDC1) is widely present on the mitochondrial outer membrane and acts as a regulator of mitochondrial autophagy in response to hypoxia, inducing Parkin-independent mitophagy (Liu et al., 2012)
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Adults Over 50 Metabolic clearance slows with age, meaning peptides stay active longer per dose
Survives transit, binds to mucosa
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