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In: Silverman H, editor
When comparing Ozempic vs Trulicity , both medications belong to the GLP-1 receptor agonist class and effectively manage type 2 diabetes, but Ozempic (semaglutide) generally provides greater A1C reduction and more significant weight loss compared to Trulicity (dulaglutide)
Some patients are genetically positioned to see results faster and may not tolerate high doses well, while others need more aggressive dosing to feel semaglutide's appetite-suppressing effects
[1] Because it is a large-protein biologic, evolocumab is not metabolized by the cytochrome P450 enzyme family
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