If they hadnt, that was well their fault
JAD helped with study design
The antioxidant capacity of silymarin can lower oxidative stress (in the liver) associated with acetaminophen metabolism in rats, which has the effect of conserving cellular glutathione levels (Campos 1989)
Am J Physiology-Lung Cell Mol Physiol 309:L369L377 de Araujo Junior RF, da Silva Reinaldo MPO, de Castro Brito GA, de Cavalcanti Franca P, de Moura Freire MA, de Medeiros CAX, de Araujo AA (2014) Olmesartan decreased levels of IL-1 and TNF-, down-regulated MMP-2, MMP-9, COX-2, RANK/RANKL and up-regulated SOCs-1 in an intestinal mucositis model
A clinician can recommend the right form (oral, sublingual, or injection), dosing schedule, and follow-up testing to ensure treatment is safe and effective
The hyperpigmented blue color is from elongated melanocytes, giving the patch the appearance of a bruise