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How do Liraglutide and Semaglutide GLP-1 differ

Moreno and M.L

GLP-1 and Semaglutide: The Biological Mechanism GLP-1 is a hormone secreted in the gut in response to food intake

Efficacy magnitude Clinical trials show GLP-1 agonists produce substantial HbA1c reductions (typically 1.01.5% depending on agent and dose) and weight loss (515% of body weight with higher doses)

In both studies, improvements in weight associated with improved quality of life parameters, physical function and cardiometabolic risk factors [47]

Glucagon directly stimulates hepatic lipid oxidation, essentially telling the liver to burn its own fat stores for energy