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Prism 10 was used for data analysis

Kleber, H.P

The peptide does not bind to growth hormone receptors on hepatocytes, does not trigger the JAK/STAT signaling cascade, and therefore does not stimulate IGF-1 synthesis or secretion

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Orforglipron Phase 3 data demonstrates that a non-peptide oral molecule can achieve weight loss comparable to injectable semaglutide, potentially expanding patient access by removing injection barriers

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