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In addition, obesity costs the U.S

BMJ 341:c2701 Manfield JH et al (2017) Bariatric surgery or non-surgical weight loss for idiopathic intracranial hypertension

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Subcutaneous administration suffers from: Lower bioavailability Variable absorption Different pharmacokinetics Which means the systemic exposure of DSIP via subcutaneous administration is not equivalent to what is achieved with intravenous infusion

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