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Obese individuals show markedly higher ACTH, and cortisol may respond to vasopressin (AVP) and corticotropin-releasing hormone (CRH) [67, 68], whereas dose-response ACTH stimulation test may interfere to elevated cortisol level [69]

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NPJ Metab Health Dis 3(1):24 Kuhre RE et al (2018) Bile acids are important direct and indirect regulators of the secretion of appetite- and metabolism-regulating hormones from the gut and pancreas

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The glycolytic rate assay was performed using the Agilent Seahorse XF Glycolytic Rate Assay Kit (103344100

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Glutathione is manufactured inside the human body by using amino acids naturally, so it is not considered an essential nutrient

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In addition to H3K4me3, the transcriptional-repression mark histone H2AK119 mono-ubiquitination (H2AK119ub) is also involved in transcriptional regulation, always occurring together with H3K27me3 in the same chromatin regions ( Bdnf promoters I to IV, while BHBA treatment weakened the occupancy of H2AK119ub at these promoters (Figure 1D)

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GLP-1 plays an immunomodulatory role

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