semaglutide and masld GI Hepatology News Metabolic dysfunction-associated steatotic liver disease

It shifts production from pheomelanin (yellow-red, UV-damaging) to eumelanin (brown-black, UV-protective) (Barnetson et al., 2006)

doi: 10.1016/j.ibneur.2023.11.007

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Moreover, the complex pathogenesis of PD makes it a suitable target for GLP-1RAs, which modulate numerous intracellular signaling pathways, as demonstrated by in vitro and in vivo studies

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Improvement of insulin resistance : GLP-1RA was shown to improve insulin signaling in the brain and promote glucose metabolism