These range from IV (intravenous) glutathione to different oral forms of glutathione to transdermal
In the case of alcohol the mechanism is well described: ethanol metabolism involving the CYP2E1 enzyme releases free radicals, and these reduce the level of reduced glutathione in the liver (Lieber, Drug Metabolism Reviews 2004, PMID 15554233)
GST isoforms (GSTM1, GSTP1, GSTT1) are expressed in the cytosol, mitochondria, and nucleus across multiple organs, including the liver, kidneys, lungs, brain, and placenta, exhibiting broad substrate specificity against electrophiles (molecules deficient in electron pairs) and ROS (2733)
You reconstitute it with bacteriostatic water, then inject subcutaneously
Selenium and asthma
No clinical trial has tested this specific combination, but the theoretical basis for synergy is compelling