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4.3 Dipeptidyl peptidase-4 enzyme inhibitors Glucagon-like peptide-1 (GLP-1) is a peptide hormone secreted by intestinal cells that stimulates insulin secretion from pancreatic cells in response to blood glucose

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Moreover, liraglutide elicited a phenotypic shift in macrophages from proinflammatory M1 to anti-inflammatory M2, while also inhibiting the expression of enzymes implicated in cartilage degradation

Sugerman HJ, Felton WL III, Sismanis A, Kellum JM, DeMaria EJ, Sugerman EL