(2004) Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury
"There are additional complex metabolites that others are looking at, so we're potentially opening a whole new interest into how cancer cells acquire nutrients and how to block that activity
Notably, when canine osteosarcoma cells D17 were treated with BI2536, the number of cells was reduced from 20%2.4% to 7.4%2% in the G0/G1 phase and increased from 18.3%2.4% to 47.2%7.7% in the G2/M phase, decreasing cell viability by up to 61.2% (P 20 H2AX foci by 59% and 107%, respectively 18 (Table 1)
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ChenTLYangHCHungCYOuMHPanYYChengMLet alImpaired embryonic development in glucose-6-phosphate dehydrogenase-deficient Caenorhabditis elegans due to abnormal redox homeostasis induced activation of calcium-independent phospholipase and alteration of glycerophospholipid metabolism
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