Packer recently proposed an intriguing hypothesis that DPP-4 inhibitors potentiate some endogenous peptides, such as stromal cell-derived factor-1, in addition to activation of GLP-1, and that unfavorable effects of those peptides on CV parameters (e.g., inflammation, fibrosis, plaque growth, and sympathetic activation) could prevail against the CV protective effects of GLP-1, possibly leading to worsened CV complications and HF [36, 37]
Those tiny air bubbles might seem harmless, and while small ones won't hurt you, they can affect dosage accuracy
Keep vials upright, protected from light (wrap in aluminum foil or use amber vials if available), and away from the freezer compartment
Advise patients who are exposed to WEGOVY during pregnancy to contact Novo Nordisk at 1-877-390-2760 or www.wegovypregnancyregistry.com [see Use in Specific Populations (8.1)]
Almost all antidepressants list hair loss as a possible side effect
& Iorizzo, M