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Other copper peptides studied include DAHK (the N-terminal copper-binding domain of human serum albumin), which has high copper affinity but primarily serves a copper transport rather than signaling function

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As the intracellular Ca 2+ concentration drops the activity of the major apical membrane Ca 2+ transporter, TRPV5, is enhanced, thus resulting in reduced luminal Ca 2+ and a reduced likelihood for renal lithiasis

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