Contrary to this, intraperitoneal administration of GLP-1 agonists does not stimulate vagal afferents 33 , only a small subset of GLP-1R-expressing vagal afferents innervate the intestinal mucosa where GLP-1 cells reside 33,34 , and ablation of vagal GLP-1R neurons doesnt prevent GLP-1Rs satiating effects 35
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You have a few excellent options for subcutaneous injections, and the best choice often comes down to personal preference, comfort, and the importance of site rotation (which we'll cover next)
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2023, www.health.harvard.edu/staying-healthy/understanding-new-weight-loss-drugs#:~:text=Two%20of%20these%20GLP%2D1.
Doll et al., 2019) as well as DHODH in mitochondria (Mao et al., 2021)