The Role of Delayed Gastric Emptying The most significant factor when combining these medications is a process called delayed gastric emptying
Pang, B., et al
Future of GLP-1 receptor agonists In a related editorial, Thiara noted that although Tang and colleagues found that GLP-1 receptor agonists and SGLT2 inhibitors had a similar effect on ADRD, the team did show that isolating semaglutide, the newest and most potent GLP-1 receptor agonist on the market, showed decreased risk of ADRD compared with SGLT2 inhibitors. Both studies had limitations, including short-term follow-up, low dementia event rates and confounding variables, Thiara wrote
Urgent specialist referral is needed if you develop neurological symptoms
Ultimately, by harnessing two powerful hormones instead of one, dual-agonist therapy offers a more robust mechanism for weight management
This approach leverages the complementary actions of insulin, which lowers fasting and post-absorptive blood sugar levels, and GLP-1 agonists, which target postprandial blood sugar levels (6)
