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The SELECT trial (N=17,604) demonstrated that semaglutide 2.4 mg reduced major adverse cardiovascular events (MACE) by 20% over a median 34.2 months in patients with overweight or obesity and pre-existing cardiovascular disease, independent of glycemic status [12]

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The liver and pancreas play crucial roles in the various stages of lipid management, including digestion, absorption, production, and distribution within the body [20]

doi: 10.1001/jamacardio.2016.1884 64 FulcherJMihaylovaBOConnellREmbersonJBlackwellLReithCet al

PlexusDx compounded semaglutide, at $189/mo month-to-month, or from $149/mo on the 6-month plan from licensed 503A pharmacies, allows personalized formulation adjustments that may improve tolerability compared to standard dosing