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Patients on tirzepatide who choose to add glutathione typically start during the dose escalation phase (weeks 412), when weight loss velocity is highest and subjective energy dips are most common

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In contrast, trials such as ELIXA, SUSTAIN-6, AMPLITUDE-O, and EXSCEL, which included broader T2DM populations without established CVD, did not show similar MI reductions [15, 17, 19, 23]

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De Palma G, Blennerhassett P, Lu J, Deng Y, Park AJ, Green W, et al