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The large UK Caucasian HT case control cohort study demonstrated clear differences in association within the HLA class II region between Hashimoto's thyroiditis and Graves' disease, differences in HLA class II genotype may, in part, contribute to the different immunopathological processes and clinical presentation of these related diseases (15a)
Modulation of stem cell fate in intestinal homeostasis, injury and repair
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These drugs, widely used for diabetes management and weight loss, have been linked by plaintiffs to serious conditions such as gastroparesis, severe vomiting, and bowel obstruction
To investigate the impact of shifting from cystine-driven to GSH-driven cysteine supply in cancer cells in an unbiased manner, we performed a multifunctional approach to pharmacological screening (MAPS) with a library of 240 metabolic inhibitors (Fig