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In vascular smooth muscle cells (VSMCs), it disrupts the TCA cycle and provokes ROS production, leading to cellular hypertrophy and phenotypic switching, which culminates in pathological thickening of the vascular wall [102]

Primary Cellular Pathways Triple Incretin Receptor Activation Metabolic Regulation GLP3 functions as a triple agonist simultaneously activating GLP-1R, GIPR, and GCGR with distinct potency profiles[1]

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[13] Tyrosinase is directly inhibited through chelation of the copper site by the thiol group

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Anti-Inflammatory Action Chronic inflammation of the scalp can inhibit follicle function and lead to miniaturisation, the process by which hair becomes progressively thinner