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10.1038/ajg.2015.301 Am

For instance, the flavonoid luteolin directly binds NGF and potentiates TrkA receptor signaling, and when combined with low-dose NGF, it mimics the effects of a high dose of NGF and promotes neurite outgrowth (Xiong Gao et al., 2021)

In the occipital cortexa region associated with visual processing and also implicated in emotional regulationglutathione concentrations were significantly lower in individuals with MDD compared to controls

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These effects are particularly relevant for people living with obesity-related metabolic conditions