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For the maintenance treatment of vitamin B12 deficiency, the usual dose is 100mcg SC/IM, given once per month

Researchers observed that intra-articular administration was associated with changes in cartilage matrix composition and chondrocyte activity markers in the treated joints compared to controls [3]

The preclinical evidence base is substantial

You may also be more likely to develop vitamin B-12 deficiency if you have: Atrophic gastritis, in which your stomach lining has thinned Pernicious anaemia, which makes it hard for your body to absorb vitamin B12 Conditions that affect your small intestine, such as Crohns disease, celiac disease, bacterial growth, or a parasite Immune system disorders, such as Graves disease or lupus Been taking certain medications that interfere with the absorption of B12

With vitamin B12 injections, you will likely stick with your treatment schedule

Inject on the same day each week, at approximately the same time