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Why It Happens So Often GLP-1s do an excellent job of reducing appetite and slowing digestion , but: They dont always address insulin resistance directly They often dont stimulate energy expenditure They rarely support nutrient partitioning or GIP/amylin balance The result

Anyone with a history of diabetic ketoacidosis (DKA) or at very high DKA risk should avoid GLP-1 therapy

While this matters less for weekly formulations than it would for daily ones, it still disrupts the predictability of your side effect and appetite suppression patterns

It can certainly be pretty stigmatizing

Prescribing decisions rest with those independent clinicians, not with the platform

Higher doses (9 mg and 25 mg) cost $299 per month