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Over half of patients stop taking GLP-1s, often because insurers stop covering them when people achieve their weight loss goals, they cant afford out-of-pocket costs, or because they experience gastroenterological side effects
Although part of the stomach is removed to reduce its volume, it can still stretch over time, potentially leading to increased appetite
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While most studies demonstrate improvement in weight or BMI on treatment (114122), trials of longer duration that may need to be combined with co-interventions are needed to address its long-term effects on body mass and metabolic health
JAMA 280 , 15961600 (1998)
When it hits the stomach, stomach acid and digestive enzymes can break it down into its individual amino acids before it ever reaches your bloodstream
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