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Originally developed as antimalarial drugs, these compounds inhibit autophagy by blocking autophagosome-lysosome fusion, thereby preventing the degradation of autophagic cargo

Dynorphin, a short opioid peptide, retains disorder when bound to the kappa opioid receptor, 77 and mobility of neurotensin residue Tyr-11 is required for activation of the cognate receptor

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I even found a few new studies on the anti-inflammatory response in this class of medications

10.1038/s41594-017-0008-2 51 GoyalB.TushirS.SharmaA.SinghS.TatuU.PandeyK.et al (2025)

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