Studies have shown that system xCT was mainly located in tubular cells, and its inhibition resulted in a rapid decline in GSH levels, which may accelerate AKI (Su et al., 2019)
Author contributions CX conceived the research plans and supervised the experiments
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Plasma half-life in animal studies is approximately 4 hours after subcutaneous administration
Up-regulation of gamma-glutamylcysteine synthetase activity in melphalan-resistant human multiple myeloma cells expressing increased glutathione levels
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