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Pharmacopeia guidelines typically impose a 28-day limit for opened multi-dose injectables to minimize contamination and stability issues

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Mol Cell Endocrinol 297(12):127136 Horsch D, Gke R, Eissele R et al (1997) Reciprocal cellular distribution of glucagon-like peptide-1 (GLP-1) immunoreactivity and GLP-1 receptor mRNA in pancreatic islets of rat

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This includes changes in energy levels, attraction, and desire for sex

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Tirzepatide belongs to a newer class of dual-action GLP-1 receptor agonists and glucose-dependent insulinotropic peptide (GIP) receptor agonists that require once-weekly injection dosing to achieve therapeutic benefit

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Pregnant or nursing women should consult with their healthcare provider before starting any new treatment

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