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Description

We found that Dihexa-mediated protection requires activation of Akt, TOR, and MEK signaling, as inhibition of any of these targets attenuates Dihexa-mediated protection

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Figure 28 shows a correlation between the blockade of HGF dimerization and HGF binding affinity and the ability to prevent MDCK cell scattering

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Preclinical studies show promise for healing and neuroprotection, but human trials are ongoing or anecdotal

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