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2) decreases anti-apoptotic levels of caspase-3 and -9

Microglia populate the CNS during early embryogenesis and primarily function in the phagocytosis of cellular debris, synaptic pruning during neurodevelopment and maturation, and the release of cytokines and growth factors that influence neuronal survival and plasticity (Ginhoux and Prinz, 2015)

The adduct was purified by size-exclusion chromatography and concentrated to ~10 mg ml 1