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TGF-B has been shown to induce cell death in the rat prostate25 and its receptor has also been found to be down regulated by androgens in this tissue.26 In the immature rat penis, TGF-B1 mRNA is under negative regulation by androgens (Lin, Rajfer, Gonzalez-Cadavid, unpublished)

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In conclusion, the results of this study demonstrate that intraperitoneal administration of NAC prevents NTG-like retinal degeneration by increasing the GSH levels and suppressing oxidative stress and autophagy in EAAC1 KO mice, but not in GLAST KO mice