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No serious adverse events related to skin sensitivity were documented, and no participants discontinued treatment solely because of this side effect

This makes it easier to inject into the tissue just under the skin

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Yet, as O'Donnell notes, on-again-off-again use is already in the cultural zeitgeist

No new or unexpected safety signals emerged beyond what we know from GLP-1 and dual-agonist therapies

Baseline LDL was 112.8mg/dl for the trial and doing the math, that means by the end of the trial the average LDL was 90mg/dl