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Alterations in one-carbon and thiol metabolism, including increased cystathionine and choline alongside decreased 5-methyl-THF and 2-hydroxybutyrate, are consistent with pathway-level shifts centered on glutathione turnover, suggesting variation in redox capacity prior to intervention

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Oxygen accelerates copper oxidation, which destabilizes the GHK-Cu complex

If this process is impacted, it can lead to low cysteine levels and elevated homocysteine levels

10.2174/092986707779313345 Curr Med Chem

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