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an exaggerated appearance of gastric lesions was noted in control diabetic rats

Test results showed that the oral administration of PNE mediated a decrease in the abundance of Streptococcus intestinalis and an increase in the transgenic metabolite l-arginine, which further inhibited osteoblasts and enhanced osteoclasts through the gutbone axis, exerting a significant anti-osteoporotic effect

After a month, patients will attend a follow-up appointment to track their progress and make any necessary changes to their weight loss program

doi: 10.1038/90984

Given their inherent and sustained migratory capacity toward inflammatory and tumor sites, mononuclear phagocytes, particularly macrophages, offer a potential strategy to overcome this limitation (198)