Clinicians should educate individuals about the potential interactions between these substances and GLP-1s and routinely screen for substance use using validated short tools such as those proposed by the Institute of Medicine for Social and Behavioral Determinants of Health [188]
A study by Xcenda found that only about 40 diabetes, weight loss, endocrine, and metabolic drugs had been excluded from at least one pharmacy benefit manager (PBM) formulary in 2014
To Maintain Weight Loss Microdosing is common after patients have used higher doses of a GLP-1 to reach their target weight in order to help with weight maintenance, says Sharon Giese, MD, a New York City plastic surgeon who has been prescribing GLP-1s since 2022
Any supplement use should be disclosed to healthcare providers to ensure comprehensive medication review and safety monitoring
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