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Using a new sterile needle, allowing the alcohol to dry fully, rotating injection sites, keeping the hands steady, and administering the medication slowly may improve comfort

The reviewer DL declared a shared parent affiliation with the authors to the handling editor at the time of review

Medscape Emedicine website

PMID 8392067

Vitamin deficiency has also been shown to provide psychological symptoms as well including feelings of depression, irritability, and other significant changes in behavior