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In Prp-TDP-43 A315T mice, dysregulated expression of estrogen-related enzymes (CYP19A1 and CYP3A4) was observed relative to wild-type controls, which suggested that toxic phosphorylated TDP-43 oligomers may disrupt the balance between CYP19A1 and CYP3A4 expression, resulting in reduced estrogen biosynthesis and accelerated degradation

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This marked the first organized physician delegation from Ukraine to participate in MSKs International Observer Program, reflecting the value of global collaboration and knowledge exchange in advancing cancer care worldwide

Take 1-2 capsules daily with water, preferably before your main meal

The small sample size in our study is a major limitation

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