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A 2024 Nature Communications study (Wang et al., including NIH scientist Nora Volkow) analyzed real-world records from 83,825 patients and found semaglutide associated with a 50 to 56% lower rate of alcohol use disorder incidence and recurrence compared with other anti-obesity medications

Glucagon-like peptide-1 receptor agonists for non-alcoholic fatty liver disease in type 2 diabetes: a meta-analysis

The Risks of Trying GLP-1 Microdosing Without Medical Guidance GLP-1 microdosing may be discussed as a lower-intensity option, but trying it without clinical oversight can increase risk

Catherine Varney, the obesity medicine director for UVA Health, the health system affiliated with the University of Virginia in Charlottesville

Neuroinflammation reduction

It does this by acting on a number of hormone pathways implicated in appetite and metabolism