The MHRA has issued public warnings about the sale of unlicensed peptides and research chemicals marketed for human use, noting that such products may be mislabelled, contaminated, or of unknown potency
No dosing, administration, clinical, or human-use guidance
Diarrhea occurs in approximately 30% of patients taking semaglutide 2.4 mg (Wegovy) and 19-23% of patients taking tirzepatide (Zepbound) according to FDA prescribing information
Additionally, approximately 20.9% of retatrutide users at 12 mg experienced dysesthesia (skin sensitivity/tingling), a side effect not seen with tirzepatide
Lyophilized (freeze-dried) peptide has excellent shelf life when stored properly, typically 12 to 24 months in a cool, dark environment
Fetissov et al., 2002