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Combined with Lion's Mane's NGF-stimulating activity, this creates a synergistic approach: Lion's Mane stimulates NGF expression, while ALCAR provides the neuronal energy and acetylcholine precursor support required for neurons to utilise that NGF signal.*

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Due to the heterogeneity presented in the included studies, (I 2 = 82%, P = 0.0008), we used the random effects model (Fig

The effects of momentary loneliness and COVID-19 stressors on hypothalamic-pituitary adrenal (HPA) axis functioning: A lockdown stage changes the association between loneliness and salivary cortisol