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While short-term use may cause only transient effects, prolonged supraphysiological IGF-1 receptor activation could potentially cause unwanted tissue growth including cardiac hypertrophy, which at extreme levels could impair cardiac function, and growth of other organs

Hodgman MJ, Garrard AR

Gut microbiota-derived components and metabolites in the progression of non-alcoholic fatty liver disease (NAFLD) [J]

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