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Researchers observed that upon binding the IRR, ARA-290 initiates signaling through JAK2 and downstream pathways including STAT3 and NF-B modulation, distinct from the STAT5-dominant signaling of classical EPO receptor activation

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Olympia Competitive placings [edit] 1992 Gold Gym Worcester Bodybuilding Championships 2nd 1996 NPC Nationals, 1st place Heavyweight (earned IFBB pro card) 1998 IFBB Night of Champions 11th 1999 Arnold Schwarzenegger Classic 4th 1999 IFBB Ironman Pro Invitational 3rd 1999 Mr