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This is the first large-scale, real-world body-composition comparison of the two market-leading GLP-1 drugs outside the trial environment and it tilts the muscle-preservation question more sharply toward semaglutide than the SURMOUNT and STEP DXA substudies suggested

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Giugliano D, Scappaticcio L, Longo M, Caruso P, Maiorino MI, Bellastella G, Ceriello A, Chiodini P, Esposito K

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